Nitrofurazone, 2-((5-nitro-2-furanyl)methylene)hydrazinecarboxamide, chemical formula C6H6N4O4, is a pale yellow crystalline compound.
This bactericidal compound is used as an antibiotic most commonly in the form of ointments. Its use in medicine has become less frequent as safer and more effective products have become availablecitation needed.
Other names for this chemical include nitrofural' and furacilin.
Synthesis
Stillman, W. B.; Scott, A. B.; 1947, U.S. Patent 241,664.
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Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01)
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Alveo-
late |
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Apicom-
plexa
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Conoidasida/
(Coccidiostats)
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Cryptosporidiosis
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thiazole (Nitazoxanide)
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Isosporiasis
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Trimethoprim/sulfamethoxazole#
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Toxoplasmosis
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Pyrimethamine • Sulfadiazine
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Aconoidasida
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Malaria
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Individual
agents
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Hemozoin
inhibitors
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Aminoquinolines
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(4-): Amodiaquine# • Chloroquine# • Hydroxychloroquine
(8-): Primaquine# • Pamaquine
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4-methanolquinolines
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Mefloquine#• Quinine# • Quinidine
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Other
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Lumefantrine (combined with artemether)
Halofantrine
Pyronaridine
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Antifolates
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DHFR inhibitors
(antifols)
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2,4-Diaminopyrimidines (pyrimethamine)
biguanides (proguanil# • chlorproguanil)
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Sulfonamides
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Sulfadoxine • sulfamethoxypyrazine
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Coformulation
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Fansidar# (sulfadoxine/pyrimethamine)
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Sesquiterpene
lactones
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Artemether# • Artesunate#• Dihydroartemisinin •
Arteether/Artemotil • Artemisinin
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Other
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Atovaquone (as Malarone)
Tetracycline • Doxycycline#
Clindamycin
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Combi-
nations
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Fixed-dose (coformulated) ACTs
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artemether-lumefantrine#
artesunate-amodiaquine (ASAQ)
artesunate-mefloquine (ASMQ)
dihydroartemisinin-piperaquine
artesunate-pyronaridine
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Other combinations
(not co-formulated)
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artesunate/SP • artesunate/mefloquine •
quinine/tetracycline • quinine/doxycycline • quinine/clindamycin
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Babesiosis
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Clindamycin
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Cilio-
phora
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Balantidiasis: Tetracycline
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Hetero-
kont |
Blastocystosis: Metronidazole
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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Otologicals (S02)
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| Anti-infectives |
Acetic acid • Aluminium acetotartrate • Boric acid • Chloramphenicol • Chlorhexidine • Ciprofloxacin • Clioquinol • Gentamicin • Hydrogen peroxide • Miconazole • Neomycin • Nitrofurazone • Ofloxacin • Polymyxin B • Rifamycin • Tetracycline
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| Corticosteroids |
Betamethasone • Dexamethasone • Fluocinolone acetonide • Hydrocortisone • Prednisolone
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| Analgesics and anesthetics |
Lidocaine • Cocaine • Phenazone
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